Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.57 |
| ▸ | HTR3B | O95264 | 2/20 | 0.57 |
| ▸ | HTR3A | P46098 | 2/20 | 0.57 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.57 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.57 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.49 |
| ▸ | SCN1A | P35498 | 1/20 | 0.45 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.45 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7301306 | 0.98 | KMT2A (0.56) | CYP2D6MEN1KMT2ACYP1A2HTR3E | |
| SCHEMBL23407877 | 0.84 | KMT2A (0.48) | CYP2D6MEN1KMT2ASCN1ASCN2A | |
| SCHEMBL23407892 | 0.83 | ATM (0.54) | CYP2D6MEN1KMT2ACYP1A2HTR3E | |
| SCHEMBL27815808 | 0.83 | MEN1 (0.60) | CYP2D6MEN1KMT2ACYP1A2HTR3E | |
| SCHEMBL112021 | 0.79 | MEN1 (0.56) | CYP2D6MEN1KMT2ACYP1A2HTR3E | |
| SCHEMBL11100418 | 0.79 | SCN1A (0.72) | CYP2D6MEN1KMT2ACYP1A2HTR3E | |
| SCHEMBL13415419 | 0.78 | MEN1 (0.55) | CYP2D6MEN1KMT2ACYP1A2HTR3E | |
| SCHEMBL16015361 | 0.78 | MEN1 (0.55) | CYP2D6MEN1KMT2ACYP1A2HTR3E | |
| SCHEMBL1689459 | 0.78 | CYP1A2 (0.55) | CYP2D6MEN1KMT2ACYP1A2HTR3E | |
| SCHEMBL7302350 | 0.78 | CHRNA7 (0.63) | CYP2D6MEN1KMT2ACYP1A2HTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5252570-A | Amidino and guanidino derivatives | B.I. ITALIA (IT) | 1993-10-12 | — | — | US | disclosed |
| US-5047410-A | Indolyl derivatives and their use as 5-HT3, receptor antagonists | ISTITUTO DE ANGELI S.P.A. (IT) | 1991-09-10 | — | — | US | disclosed |
| EP-0351385-A2 | New amidino and guanidino derivatives | BOEHRINGER INGELHEIM ITALIA S.p.A. (IT) | 1990-01-17 | — | — | EP | disclosed |