Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.62 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.62 |
| ▸ | HTR3B | O95264 | 2/20 | 0.62 |
| ▸ | HTR3A | P46098 | 2/20 | 0.62 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.62 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7295304 | 0.81 | CHRNA7 (0.63) | CHRNA7MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL221269 | 0.78 | CHRNA7 (1.00) | CHRNA7MEN1KMT2AHTR3EHTR3B | |
| SCHEMBL7301448 | 0.78 | CYP2D6 (0.57) | MEN1KMT2ACYP1A2CYP2D6HTR3E | |
| SCHEMBL1103724 | 0.78 | CHRNA7 (1.00) | CHRNA7MEN1KMT2AHTR3EHTR3B | |
| Tropanserin SCHEMBL467253 | 0.77 | CYP2D6 (1.00) | CHRNA7MEN1KMT2ACYP1A2CYP2D6 | |
| Tropanserin SCHEMBL29385911 | 0.77 | CYP2D6 (1.00) | CHRNA7MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL27815808 | 0.77 | MEN1 (0.60) | MEN1KMT2ACYP1A2CYP2D6HTR3E | |
| Hydrochloric Acid SCHEMBL7301306 | 0.76 | KMT2A (0.56) | MEN1KMT2ACYP1A2CYP2D6HTR3E | |
| Tropanserin SCHEMBL29400878 | 0.76 | CYP2D6 (0.97) | CHRNA7MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL31544490 | 0.76 | KMT2A (0.81) | CHRNA7MEN1KMT2ACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5252570-A | Amidino and guanidino derivatives | B.I. ITALIA (IT) | 1993-10-12 | — | — | US | disclosed |
| EP-0351385-A2 | New amidino and guanidino derivatives | BOEHRINGER INGELHEIM ITALIA S.p.A. (IT) | 1990-01-17 | — | — | EP | disclosed |