Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.70 |
| ▸ | LMNA | P02545 | 4/20 | 0.70 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.54 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22192691 | 0.92 | NPC1 (0.65) | MAPTSMN1; SMN2LMNAPOLBNPC1 | |
| SCHEMBL22192234 | 0.87 | NPC1 (0.59) | MAPTSMN1; SMN2LMNAPOLBNPC1 | |
| SCHEMBL7294882 | 0.87 | MAPT (0.65) | MAPTSMN1; SMN2LMNATRPV1POLB | |
| SCHEMBL7302201 | 0.87 | NPC1 (0.74) | MAPTSMN1; SMN2LMNATRPV1POLB | |
| SCHEMBL12412550 | 0.87 | SMN1; SMN2 (0.65) | MAPTSMN1; SMN2LMNAPOLBKDM4E | |
| SCHEMBL22192244 | 0.85 | MAPT (0.57) | MAPTSMN1; SMN2LMNAPOLBNPC1 | |
| SCHEMBL22192245 | 0.85 | NPC1 (0.60) | MAPTSMN1; SMN2LMNAPOLBNPC1 | |
| SCHEMBL7302398 | 0.84 | SMN1; SMN2 (0.72) | MAPTSMN1; SMN2LMNATRPV1NPC1 | |
| SCHEMBL21588706 | 0.82 | MEN1 (0.64) | MAPTLMNATRPV1POLBNPC1 | |
| SCHEMBL9695914 | 0.82 | MAPT (0.73) | MAPTSMN1; SMN2LMNATRPV1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358118-B1 | Phenylamides - process for their preparation as well as a drug containing those compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-5135949-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-04 | — | — | US | disclosed |
| EP-0358118-A1 | Phenylamides - process for their preparation as well as a drug containing those compounds | Roche Diagnostics GmbH (DE) | 1990-03-14 | — | — | EP | disclosed |