Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.72 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.68 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.68 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.60 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22192690 | 0.90 | KMT2A (0.72) | SMN1; SMN2KMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL7302201 | 0.86 | NPC1 (0.74) | SMN1; SMN2NR1H4EPHX2TRPV1KMT2A | |
| SCHEMBL10428818 | 0.86 | NPC1 (0.74) | SMN1; SMN2KMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL21588757 | 0.85 | KMT2A (0.65) | NR1H4KMT2AMEN1HDAC3HDAC11 | |
| SCHEMBL7291792 | 0.85 | NR1H4 (0.69) | SMN1; SMN2NR1H4TRPV1KMT2AMEN1 | |
| SCHEMBL1283871 | 0.85 | SMN1; SMN2 (1.00) | SMN1; SMN2NR1H4EPHX2KMT2AMEN1 | |
| SCHEMBL21588706 | 0.84 | MEN1 (0.64) | TRPV1KMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL7301532 | 0.84 | MAPT (0.70) | SMN1; SMN2NR1H4EPHX2TRPV1KMT2A | |
| SCHEMBL22192225 | 0.84 | KMT2A (0.66) | SMN1; SMN2KMT2AMEN1ALDH1A1NPC1 | |
| Hydrochloric Acid SCHEMBL4640626 | 0.83 | SMN1; SMN2 (0.96) | SMN1; SMN2NR1H4EPHX2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358118-B1 | Phenylamides - process for their preparation as well as a drug containing those compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-5135949-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-04 | — | — | US | disclosed |