Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 3/20 | 0.36 |
| ▸ | EBP | Q15125 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 8/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306036 | 0.93 | EBP (0.41) | CACNA1BEBPSIGMAR1CHRM3 | |
| SCHEMBL7313731 | 0.92 | CACNA1B (0.38) | CACNA1BEBPSIGMAR1CHRM3ABCB1 | |
| SCHEMBL7319369 | 0.92 | EPHX1 (0.34) | CACNA1BEBPSIGMAR1CHRM3KCNH2 | |
| SCHEMBL7302652 | 0.91 | EBP (0.37) | CACNA1BEBPSIGMAR1 | |
| SCHEMBL7310708 | 0.91 | EBP (0.36) | CACNA1BEBPSIGMAR1 | |
| SCHEMBL7309476 | 0.91 | EBP (0.36) | CACNA1BEBPSIGMAR1CACNA1G | |
| SCHEMBL7315131 | 0.91 | EBP (0.36) | CACNA1BEBPSIGMAR1 | |
| SCHEMBL7317799 | 0.90 | EBP (0.36) | CACNA1BEBPSIGMAR1CHRM3ABCB1 | |
| SCHEMBL7314456 | 0.89 | ABCB1 (0.42) | CACNA1BEBPSIGMAR1LMNAABCB1 | |
| SCHEMBL7309172 | 0.88 | EBP (0.35) | CACNA1BEBPSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |