Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 3/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | EBP | Q15125 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | EED | O75530 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311070 | 0.93 | CACNA1B (0.38) | CACNA1BSIGMAR1EBPCHRM2CHRM3 | |
| SCHEMBL7315000 | 0.92 | EPHX1 (0.39) | CACNA1BSIGMAR1EBPCHRM2CHRM3 | |
| SCHEMBL7301603 | 0.92 | CACNA1B (0.36) | CACNA1BSIGMAR1EBPCHRM2CHRM3 | |
| SCHEMBL7306036 | 0.91 | EBP (0.41) | CACNA1BSIGMAR1EBPCHRM3 | |
| SCHEMBL7316806 | 0.90 | EBP (0.37) | CACNA1BSIGMAR1EBPCHRM2CHRM1 | |
| SCHEMBL7305376 | 0.90 | EBP (0.37) | CACNA1BSIGMAR1EBPCHRM3 | |
| SCHEMBL7317234 | 0.89 | EBP (0.37) | CACNA1BSIGMAR1EBPCHRM2CHRM3 | |
| SCHEMBL7317745 | 0.89 | EBP (0.37) | CACNA1BSIGMAR1EBPCHRM2CHRM3 | |
| SCHEMBL7310134 | 0.89 | EBP (0.37) | CACNA1BSIGMAR1EBPCHRM2CHRM3 | |
| SCHEMBL7316004 | 0.89 | EPHX1 (0.37) | SIGMAR1EBPMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |