Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6044463 | 0.83 | HSD17B10 (0.46) | MAOBMAOANPC1HPGDRAB9A | |
| SCHEMBL16000138 | 0.81 | MAOB (0.51) | MAOBMAOAALDH1A1NPC1HPGD | |
| SCHEMBL7312575 | 0.80 | KMT2A (0.45) | ALDH1A1NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL20171129 | 0.76 | HPGD (0.54) | MAOBMAOAALDH1A1NPC1HPGD | |
| SCHEMBL11011195 | 0.75 | SMPD1 (0.54) | NPC1HPGDRAB9ASMN1; SMN2LMNA | |
| SCHEMBL6044447 | 0.74 | MAOB (0.50) | MAOBMAOAALDH1A1NPC1HPGD | |
| SCHEMBL22882767 | 0.73 | KMT2A (0.46) | MAOBMAOAALDH1A1NPC1HPGD | |
| SCHEMBL11123825 | 0.72 | KDM4E (0.44) | ALDH1A1NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL6044542 | 0.72 | MAOB (0.50) | MAOBMAOAALDH1A1NPC1HPGD | |
| SCHEMBL4909097 | 0.71 | HSD17B10 (0.45) | MAOBMAOAALDH1A1NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0678503-B1 | Delta-amino-gamma-hydroxy-omega-aryl alkanoic acid amides with enzyme especially renin inhibiting activities | NOVARTIS AG (CH) | 1999-09-01 | — | — | EP | disclosed |
| EP-0678503-A1 | Delta-amino-gamma-hydroxy-omega-aryl alkanoic acid amides with enzyme especially renin inhibiting activities | CIBA-GEIGY AG (CH) | 1995-10-25 | — | — | EP | disclosed |