Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | PAM | P19021 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7302039 | 1.00 | HTR2A (0.46) | HTR2ACYP1A2CNR2MAOBGRIK1 | |
| SCHEMBL27669816 | 1.00 | HTR2A (0.46) | HTR2ACYP1A2CNR2MAOBGRIK1 | |
| SCHEMBL27396191 | 0.81 | HTR2A (0.47) | HTR2ACYP1A2CNR2MAOBGRIK1 | |
| SCHEMBL14146002 | 0.81 | HTR2A (0.47) | HTR2ACYP1A2CNR2MAOBGRIK1 | |
| SCHEMBL24658442 | 0.80 | APP (0.37) | — | |
| SCHEMBL1760250 | 0.80 | MAPT (0.47) | GRIK1GRIK2 | |
| SCHEMBL1760216 | 0.80 | MAPT (0.47) | GRIK1GRIK2 | |
| SCHEMBL1760249 | 0.80 | MAPT (0.47) | GRIK1GRIK2 | |
| SCHEMBL27510946 | 0.79 | SLC15A1 (0.42) | HTR2ACYP1A2CNR2 | |
| SCHEMBL11652804 | 0.79 | CYP1A2 (0.49) | HTR2ACYP1A2CNR2GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520336-A2 | Aldehyde derivatives and their use as calpain inhibitors | FUJIREBIO Inc. (JP) | 1992-12-30 | — | — | EP | disclosed |