Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7293570 | 0.93 | REN (0.61) | REN | |
| SCHEMBL7299838 | 0.92 | REN (0.60) | REN | |
| SCHEMBL7299423 | 0.91 | REN (0.63) | REN | |
| SCHEMBL7292733 | 0.88 | REN (0.63) | REN | |
| SCHEMBL7293439 | 0.87 | REN (0.62) | REN | |
| SCHEMBL9699556 | 0.83 | REN (0.57) | REN | |
| SCHEMBL7295213 | 0.82 | REN (0.58) | REN | |
| SCHEMBL7368073 | 0.81 | REN (0.58) | REN | |
| SCHEMBL7266883 | 0.81 | REN (0.57) | REN | |
| SCHEMBL9770970 | 0.78 | REN (0.60) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0339483-A2 | Renin inhbiting amino-acid derivatives | MERCK PATENT GmbH (DE) | 1989-11-02 | — | — | EP | disclosed |