Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 15/20 | 0.52 |
| ▸ | AGTR2 | P50052 | 10/20 | 0.51 |
| ▸ | EDNRA | P25101 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7312288 | 0.91 | AGTR1 (0.56) | AGTR1AGTR2EDNRA | |
| SCHEMBL8847539 | 0.90 | AGTR1 (0.58) | AGTR1AGTR2EDNRA | |
| SCHEMBL9042243 | 0.90 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL7308872 | 0.89 | AGTR1 (0.65) | AGTR1AGTR2 | |
| SCHEMBL7303480 | 0.88 | AGTR1 (0.57) | AGTR1AGTR2EDNRA | |
| SCHEMBL7305018 | 0.87 | AGTR1 (0.61) | AGTR1AGTR2EDNRA | |
| SCHEMBL7311522 | 0.87 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL683384 | 0.85 | AGTR1 (0.70) | AGTR1AGTR2 | |
| SCHEMBL7304497 | 0.84 | AGTR1 (0.59) | AGTR1AGTR2 | |
| SCHEMBL8792314 | 0.83 | AGTR1 (0.56) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0502314-A1 | Benzimidazol, medicaments containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-09-09 | — | — | EP | disclosed |