Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.38 |
| ▸ | DRD3 | P35462 | 3/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | DRD1 | P21728 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7302193 | 1.00 | FNTA (0.46) | FNTAFNTBCHRM2ADRA2ACYP2D6 | |
| SCHEMBL7303847 | 0.87 | FNTA (0.44) | FNTAFNTBCHRM2ADRA2ACYP2D6 | |
| SCHEMBL7303850 | 0.87 | FNTA (0.44) | FNTAFNTBCHRM2ADRA2ACYP2D6 | |
| SCHEMBL7303180 | 0.87 | SETD7 (0.48) | FNTAFNTBCHRM2ADRA2ACYP2D6 | |
| SCHEMBL7303176 | 0.87 | SETD7 (0.48) | FNTAFNTBCHRM2ADRA2ACYP2D6 | |
| Hydrochloric Acid SCHEMBL9245652 | 0.86 | SETD7 (0.47) | FNTAFNTBCHRM2ADRA2ACYP2D6 | |
| Hydrochloric Acid SCHEMBL9245646 | 0.86 | SETD7 (0.47) | FNTAFNTBCHRM2ADRA2ACYP2D6 | |
| SCHEMBL7308567 | 0.85 | FNTA (0.44) | FNTAFNTBCHRM2ADRA2ACYP2D6 | |
| SCHEMBL7308575 | 0.85 | FNTA (0.44) | FNTAFNTBCHRM2ADRA2ACYP2D6 | |
| SCHEMBL7439213 | 0.83 | FNTA (0.47) | FNTAFNTBLMNACYP3A4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0479601-B1 | Piperidine derivatives and their use as antiarrhythmic agents | AJINOMOTO KK (JP) | 1999-12-15 | — | — | EP | claimed |
| EP-0479601-B1 | Piperidine derivatives and their use as antiarrhythmic agents | AJINOMOTO KK (JP) | 1999-12-15 | — | — | EP | disclosed |
| US-5229400-A | Cardiovascular disorders | AJINOMOTO CO., INC. (JP) | 1993-07-20 | — | — | US | disclosed |
| EP-0479601-A2 | Piperidine derivatives and their use as antiarrhythmic agents | Ajinomoto Co., Inc. (JP) | 1992-04-08 | — | — | EP | disclosed |