Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.44 |
| ▸ | FNTB | P49356 | 1/20 | 0.44 |
| ▸ | TCF4 | P15884 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7303847 | 1.00 | FNTA (0.44) | FNTAFNTBTCF4CTNNB1MAPK1 | |
| SCHEMBL7310123 | 0.88 | TCF4 (0.47) | TCF4CTNNB1MAPK1CHRM2HTR1A | |
| SCHEMBL7306999 | 0.88 | TCF4 (0.48) | FNTAFNTBTCF4CTNNB1MAPK1 | |
| SCHEMBL7306992 | 0.88 | TCF4 (0.48) | FNTAFNTBTCF4CTNNB1MAPK1 | |
| SCHEMBL7302193 | 0.87 | FNTA (0.46) | FNTAFNTBMAPK1CHRM2HTR1A | |
| SCHEMBL7302187 | 0.87 | FNTA (0.46) | FNTAFNTBMAPK1CHRM2HTR1A | |
| SCHEMBL7308575 | 0.85 | FNTA (0.44) | FNTAFNTBMAPK1CHRM2HTR1A | |
| SCHEMBL7308567 | 0.85 | FNTA (0.44) | FNTAFNTBMAPK1CHRM2HTR1A | |
| SCHEMBL7299791 | 0.82 | TCF4 (0.43) | TCF4CTNNB1MAPK1PTGS1PTGS2 | |
| SCHEMBL7299796 | 0.82 | TCF4 (0.43) | TCF4CTNNB1MAPK1PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5208976-A | — | — | None | — | — | JP | disclosed |
| EP-0530016-B1 | Piperidine derivative and pharmaceutical composition containing it | AJINOMOTO KK (JP) | 1995-08-02 | — | — | EP | disclosed |
| JP-H05208976-A | PIPERIDINE DERIVATIVE AND ANTIHYPERTENSIVE AGENT CONTAINING THE SAME DERIVATIVE | AJINOMOTO CO INC | 1993-08-20 | — | — | JP | disclosed |
| EP-0530016-A2 | Piperidine derivative and pharmaceutical composition containing it | Ajinomoto Co., Inc. (JP) | 1993-03-03 | — | — | EP | disclosed |