SCHEMBL730222

SCHEMBL730222

CCc1cc(O)ccc1C(=O)OC

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.65
CA1 P00915 5/20 0.65
CA2 P00918 5/20 0.65
CA7 P43166 5/20 0.65
CA9 Q16790 5/20 0.65
CA14 Q9ULX7 5/20 0.65
PDK2 Q15119 1/20 0.65
PDK4 Q16654 1/20 0.65
EGFR P00533 4/20 0.56
HPGD P15428 4/20 0.49
ALDH1A1 P00352 3/20 0.49
TP53 P04637 2/20 0.49
HSD17B10 Q99714 2/20 0.49
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2C9 P11712 1/20 0.49
ALOX15 P16050 1/20 0.49
ALOX12 P18054 1/20 0.49
CYP2C19 P33261 1/20 0.49
CKS1B P61024 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4039654 0.88 CA12 (0.59) CA12CA1CA2CA7CA9
SCHEMBL28691240 0.87 CA12 (0.62) CA12CA1CA2CA7CA9
SCHEMBL23540820 0.86 CA12 (0.61) CA12CA1CA2CA7CA9
SCHEMBL2318550 0.85 CA12 (0.65) CA12CA1CA2CA7CA9
SCHEMBL29288325 0.84 CA12 (0.54) CA12CA1CA2CA7CA9
SCHEMBL542402 0.84 CA12 (0.72) CA12CA1CA2CA7CA9
SCHEMBL7261273 0.83 TP53 (0.55) CA12CA1CA2CA7CA9
SCHEMBL607262 0.83 ALDH1A1 (0.50) CA12CA1CA2CA7CA9
SCHEMBL6286525 0.83 CA12 (0.57) CA12CA1CA2CA7CA9
SCHEMBL10614787 0.83 CA12 (0.57) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119385745-A Antipyretic hydrogel, preparation method and application thereof, and hydrogel antipyretic patch 福建博草荟药业集团有限公司 2025-02-07 CN disclosed
CN-109563052-A 5-amino-2, 3-dihydrothiazine-1, 4-dione crystals 麦翠奥制药公司 2019-04-02 CN disclosed
CN-109071461-A The method for preparing 5- amino -2,3- dihydro thiazine -1,4- diketone crystalline solid 麦翠奥制药公司 2018-12-21 CN disclosed
EP-1666473-B1 CARBOXYLIC ACID COMPOUNDS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME AS THE ACTIVE INGREDIENT ONO PHARMACEUTICAL CO (JP) 2013-01-02 EP disclosed
US-8138335-B2 Carboxylic acid compounds and medicinal compositions containing the same as the active ingredient ONO PHARMACEUTICAL CO., LTD (JP) 2012-03-20 US disclosed
US-20100029631-A1 CARBOXYLIC ACID COMPOUNDS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME AS THE ACTIVE INGREDIENT ONO PHARMACEUTICAL CO., LTD. (JP) 2010-02-04 US disclosed
US-7601712-B2 Such as (1)-2-(4-chloro-3-((2-chloro-4-(((2S)-4-methyl-3,4-dihydro-2H-1,4-benzoxazin-2-ly)methoxy)benzoyl)amino)phenyl)-2-methylpropanoic acid; prostaglandin receptor agonists ONO PHARMACEUTICAL CO., LTD. (JP) 2009-10-13 US disclosed
US-20080175918-A1 CHEMICALLY CROSS-LINKED ELASTOMERIC MICROCAPSULES ENGINEERED RELEASE SYSTEMS, INC. 2008-07-24 US disclosed
WO-2007009023-A2 CHEMICALLY CROSS-LINKED ELASTOMERIC MICROCAPSULES ENGINEERED RELEASE SYSTEMS, INC. (US) 2007-01-18 WO disclosed
US-20070004716-A1 Carboxylic acid compounds and medicinal compositions containing the same as the active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 2007-01-04 US disclosed
EP-1666473-A1 CARBOXYLIC ACID COMPOUNDS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME AS THE ACTIVE INGREDIENT ONO PHARMACEUTICAL CO., LTD. (JP) 2006-06-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100029631-A1 CARBOXYLIC ACID COMPOUNDS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME AS THE ACTIVE INGREDIENT GPR17, CYSLTR1, KIT CA12 1542/4885CA1 542/4885CA2 374/4885
US-20070004716-A1 Carboxylic acid compounds and medicinal compositions containing the same as the active ingredient GPR17, CYSLTR1, KIT CA12 1542/4885CA1 542/4885CA2 374/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.