SCHEMBL7302241

SCHEMBL7302241

CCOC(=O)[C@@H]1C[C@@H](O)CN1CC

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.36
MEN1 O00255 2/20 0.36
ATM Q13315 1/20 0.36
MAPT P10636 3/20 0.36
ALDH1A1 P00352 7/20 0.35
LMNA P02545 1/20 0.35
FKBP1A P62942 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7299590 1.00 KMT2A (0.36) KMT2AMEN1ATMMAPTALDH1A1
SCHEMBL7301668 1.00 KMT2A (0.36) KMT2AMEN1ATMMAPTALDH1A1
SCHEMBL7306693 1.00 KMT2A (0.36) KMT2AMEN1ATMMAPTALDH1A1
SCHEMBL7308325 1.00 KMT2A (0.36) KMT2AMEN1ATMMAPTALDH1A1
SCHEMBL11588481 0.83 MAPT (0.40) KMT2AMEN1MAPTALDH1A1LMNA
SCHEMBL464765 0.81 KMT2A (0.37) KMT2AMEN1ATMMAPTALDH1A1
SCHEMBL464766 0.81 KMT2A (0.37) KMT2AMEN1ATMMAPTALDH1A1
SCHEMBL20113215 0.81 KMT2A (0.37) KMT2AMEN1ATMMAPTALDH1A1
SCHEMBL5568192 0.79 MEN1 (0.50) KMT2AMEN1ATMMAPTALDH1A1
SCHEMBL5568190 0.79 MEN1 (0.50) KMT2AMEN1ATMMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0481756-B1 Benzamide derivatives TEIKOKU CHEM IND CO LTD (JP) 1997-07-09 EP disclosed
US-5143935-A Gastrointestinal disorders TEIKOKU CHEMICAL INDUSTRY CO., LTD. (JP) 1992-09-01 US disclosed
EP-0481756-A2 Benzamide derivatives TEIKOKU CHEMICAL INDUSTRY CO., LTD. (JP) 1992-04-22 EP disclosed