Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FCER2 | P06734 | 4/20 | 0.61 |
| ▸ | MMP1 | P03956 | 4/20 | 0.61 |
| ▸ | MMP2 | P08253 | 1/20 | 0.59 |
| ▸ | MMP3 | P08254 | 1/20 | 0.59 |
| ▸ | REN | P00797 | 2/20 | 0.59 |
| ▸ | MME | P08473 | 2/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL242142 | 0.91 | FCER2 (0.60) | FCER2MMP1MMP2MMP3REN | |
| SCHEMBL242141 | 0.91 | FCER2 (0.60) | FCER2MMP1MMP2MMP3REN | |
| SCHEMBL17132263 | 0.90 | FCER2 (0.59) | FCER2MMP1MMP2MMP3REN | |
| SCHEMBL30573682 | 0.90 | FCER2 (0.59) | FCER2MMP1MMP2MMP3REN | |
| SCHEMBL23870381 | 0.89 | FCER2 (0.61) | FCER2MMP1MMP2MMP3REN | |
| SCHEMBL7292059 | 0.89 | MME (0.71) | MMP1MMP2MMP3MME | |
| SCHEMBL15851264 | 0.89 | FCER2 (0.62) | FCER2MMP1MME | |
| SCHEMBL15851263 | 0.89 | FCER2 (0.62) | FCER2MMP1MME | |
| SCHEMBL14269021 | 0.89 | FCER2 (0.62) | FCER2MMP1MME | |
| SCHEMBL10362579 | 0.86 | FCER2 (0.65) | FCER2MMP1MMP2MMP3REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1989010751-A1 | FUNCTIONALIZED PEPTIDYL AMINODIOLS AND -TRIOLS | ABBOTT LABORATORIES (US) | 1989-11-16 | — | — | WO | disclosed |
| EP-0341602-A2 | Renin-inhibiting functionalized peptidyl aminodiols and - triols | ABBOTT LABORATORIES (US) | 1989-11-15 | — | — | EP | disclosed |