SCHEMBL242142

SCHEMBL242142

CC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(N)=O

nearest known ligand 0.60

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FCER2 P06734 3/20 0.60
MMP1 P03956 3/20 0.60
KISS1R Q969F8 1/20 0.60
GNPAT O15228 1/20 0.59
MMP2 P08253 1/20 0.58
MMP3 P08254 1/20 0.58
REN P00797 4/20 0.58
CTSS P25774 1/20 0.56
CTSK P43235 1/20 0.56
OPRD1 P41143 1/20 0.55
MME P08473 1/20 0.55
ALDH1A1 P00352 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL242141 1.00 FCER2 (0.60) FCER2MMP1KISS1RGNPATMMP2
SCHEMBL30573682 0.91 FCER2 (0.59) FCER2MMP1KISS1RMMP2MMP3
SCHEMBL17132263 0.91 FCER2 (0.59) FCER2MMP1KISS1RMMP2MMP3
SCHEMBL7302253 0.91 FCER2 (0.61) FCER2MMP1MMP2MMP3REN
SCHEMBL10049885 0.90 GNPAT (0.66) FCER2MMP1KISS1RGNPATREN
SCHEMBL30493631 0.90 GNPAT (0.66) FCER2MMP1KISS1RGNPATREN
SCHEMBL15692325 0.89 MME (0.69) GNPATMMP2CTSSCTSKMME
SCHEMBL31326264 0.89 MME (0.69) GNPATMMP2CTSSCTSKMME
SCHEMBL23870381 0.88 FCER2 (0.61) FCER2MMP1MMP2MMP3REN
SCHEMBL31326263 0.87 CTSS (0.56) MMP1GNPATMMP2MMP3REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2635281-A1 METHODS AND COMPOSITIONS FOR PREVENTION AND TREATMENT OF CARDIAC HYPERTROPHY University Of Hawaii (US) 2013-09-11 EP claimed
WO-2012061505-A1 METHODS AND COMPOSITIONS FOR PREVENTION AND TREATMENT OF CARDIAC HYPERTROPHY UNIVERSITY OF HAWAII (US) 2012-05-10 WO claimed
EP-2765190-B1 MUTANT Y-GLUTAMYLTRANSFERASE, AND METHOD FOR PRODUCING Y-GLUTAMYLVALYLGLYCINE OR SALT THEREOF AJINOMOTO KK (JP) 2018-05-23 EP disclosed
US-9677106-B2 Method for producing gamma-glutamylvalylglycine or a salt thereof AJINOMOTO CO., INC. (JP) 2017-06-13 US disclosed
US-9580696-B2 Method for producing γ-glutamylvalylglycine or a salt thereof AJINOMOTO CO., INC. (JP) 2017-02-28 US disclosed
US-20160355861-A1 METHOD FOR PRODUCING GAMMA-GLUTAMYLVALYLGLYCINE OR A SALT THEREOF AJINOMOTO CO., INC. (JP) 2016-12-08 US disclosed
US-20150352105-A1 METHODS AND COMPOSITIONS FOR PREVENTION AND TREATMENT OF CARDIAC HYPERTROPHY NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2015-12-10 US disclosed
EP-2298909-B1 Novel peptide-forming enzyme gene AJINOMOTO KK (JP) 2014-10-01 EP disclosed
EP-2298907-B1 Novel peptide-forming enzyme gene AJINOMOTO KK (JP) 2014-08-20 EP disclosed
EP-2298908-B1 Novel peptide-forming enzyme gene AJINOMOTO KK (JP) 2014-08-20 EP disclosed
EP-2765190-A1 MUTANT -GLUTAMYLTRANSFERASE, AND METHOD FOR PRODUCING -GLUTAMYLVALYLGLYCINE OR SALT THEREOF AJINOMOTO CO., INC. (JP) 2014-08-13 EP disclosed
WO-2005010196-A1 METHOD FOR PRODUCING DIPEPTIDES AJINOMOTO CO., INC. (JP) 2005-02-03 WO disclosed
US-20050019864-A1 Novel peptide-forming enzyme gene AJINOMOTO CO., INC. (JP) 2005-01-27 US disclosed
CN-1558947-A Gene of peptide-producing enzyme, and process for producing dipeptide ֮����ʽ���� 2004-12-29 CN disclosed
US-20040253665-A1 Novel peptide-producing enzyme, microbe producing the enzyme and method for dipeptide synthesis using them AJINOMOTO CO., INC. (JP) 2004-12-16 US disclosed
US-20040219631-A1 Method for producing tripeptides and/or peptides longer than tripeptides AJINOMOTO CO., INC. (JP) 2004-11-04 US disclosed
US-20040204577-A1 Novel peptide-forming enzyme gene AJINOMOTO CO., INC. (JP) 2004-10-14 US disclosed
US-20040137558-A1 Process for producing dipeptide, peptide synthase to be used therein and process for producing peptide synthase AJINOMOTO CO., INC. (JP) 2004-07-15 US disclosed
EP-1411062-A1 PROCESS FOR PRODUCING DIPEPTIDE,PEPTIDE SYNTHASE TO BE USED THEREIN AND PROCESS FOR PRODUCING PEPTIDE SYNTHASE Ajinomoto Co., Inc. (JP) 2004-04-21 EP disclosed
EP-1411116-A1 PEPTIDE SYNTHASE GENE, PEPTIDE SYNTHASE AND PROCESS FOR PRODUCING DIPEPTIDE Ajinomoto Co., Inc. (JP) 2004-04-21 EP disclosed