Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | CXCR4 | P61073 | 7/20 | 0.36 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL934393 | 0.77 | KDM4E (0.41) | KDM4ECXCR4CXCL12ALDH1A1 | |
| SCHEMBL2385806 | 0.76 | KDM4E (0.39) | KDM4ECXCR4CXCL12HRH4HRH3 | |
| SCHEMBL8360245 | 0.74 | CXCR4 (0.41) | KDM4ECXCR4CXCL12HRH4HRH3 | |
| SCHEMBL730235 | 0.73 | KDM4E (0.36) | KDM4ECXCR4CXCL12HRH4HRH3 | |
| SCHEMBL728035 | 0.71 | TSHR (0.35) | ALDH1A1 | |
| SCHEMBL17373495 | 0.70 | KDM4E (0.36) | KDM4ECXCR4CXCL12HRH4HRH3 | |
| SCHEMBL2698028 | 0.69 | KDM4E (0.54) | KDM4EMEN1GAAHTTKMT2A | |
| SCHEMBL1246156 | 0.69 | KDM4E (0.54) | KDM4EMEN1GAAHTTKMT2A | |
| SCHEMBL1246086 | 0.69 | KDM4E (0.54) | KDM4EMEN1GAAHTTKMT2A | |
| SCHEMBL3700273 | 0.68 | KDM4E (0.37) | KDM4ECXCR4CXCL12HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2393861-B1 | MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY | MOMENTIVE PERFORMANCE MAT INC (US) | 2013-10-23 | — | — | EP | claimed |
| US-8138297-B2 | Moisture-curable silylated polymer possessing improved storage stability | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2012-03-20 | — | — | US | claimed |
| US-20100204384-A1 | Moisture-curable silylated polymer possessing improved storage stability | MOMENTIVE PERFORMANCE MATERIALS INC. | 2010-08-12 | — | — | US | claimed |
| EP-2393861-B1 | MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY | MOMENTIVE PERFORMANCE MAT INC (US) | 2013-10-23 | — | — | EP | disclosed |
| US-8138297-B2 | Moisture-curable silylated polymer possessing improved storage stability | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2012-03-20 | — | — | US | disclosed |
| EP-2393861-A1 | MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY | Momentive Performance Materials Inc. (US) | 2011-12-14 | — | — | EP | disclosed |
| US-20100204384-A1 | Moisture-curable silylated polymer possessing improved storage stability | MOMENTIVE PERFORMANCE MATERIALS INC. | 2010-08-12 | — | — | US | disclosed |
| WO-2010091338-A1 | MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2010-08-12 | — | — | WO | disclosed |