SCHEMBL8360245

SCHEMBL8360245

[SiH3]O[SiH2]CCCNC1CCCCC1

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CXCR4 P61073 10/20 0.41
CXCL12 P48061 1/20 0.41
HRH3 Q9Y5N1 7/20 0.39
HRH4 Q9H3N8 6/20 0.39
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
RAD52 P43351 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17733777 0.75 CXCR4 (0.61) CXCR4CXCL12HRH3HRH4KDM4E
SCHEMBL9417435 0.75 CXCR4 (0.61) CXCR4CXCL12HRH3HRH4KDM4E
SCHEMBL730235 0.74 KDM4E (0.36) CXCR4CXCL12HRH3HRH4KDM4E
SCHEMBL730233 0.74 KDM4E (0.36) CXCR4CXCL12HRH3HRH4KDM4E
SCHEMBL10604006 0.73 CXCR4 (0.53) CXCR4CXCL12HRH3HRH4KDM4E
SCHEMBL4739261 0.73 CXCR4 (0.53) CXCR4CXCL12HRH3HRH4KDM4E
SCHEMBL4786588 0.73 CXCR4 (0.53) CXCR4CXCL12HRH3HRH4KDM4E
SCHEMBL4786617 0.73 CXCR4 (0.53) CXCR4CXCL12HRH3HRH4KDM4E
Hydrochloric Acid SCHEMBL9714202 0.73 CXCR4 (0.59) CXCR4CXCL12HRH3HRH4KDM4E
SCHEMBL841438 0.73 CXCR4 (0.53) CXCR4CXCL12HRH3HRH4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5990334-A Ionic organosilicon compounds and their preparation and use WACKER-CHEMIE GMBH (DE) 1999-11-23 US disclosed
EP-0849307-B1 Ionic organosilicon compounds, their preparation and use WACKER CHEMIE GMBH (DE) 1999-03-17 EP disclosed
EP-0849307-A1 Ionic organosilicon compounds, their preparation and use Wacker-Chemie GmbH (DE) 1998-06-24 EP disclosed