SCHEMBL730234

SCHEMBL730234

COC(CCCCNC1CCCCC1)(OC)O[SiH3]

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.38
CXCR4 P61073 7/20 0.38
CXCL12 P48061 1/20 0.37
GNAI3 P08754 2/20 0.36
GNAO1 P09471 2/20 0.36
GNAI1 P63096 2/20 0.36
HRH4 Q9H3N8 4/20 0.35
HRH3 Q9Y5N1 4/20 0.35
RAD52 P43351 1/20 0.35
ALDH1A1 P00352 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2385813 0.77 KDM4E (0.40) KDM4ECXCR4CXCL12RAD52ALDH1A1
SCHEMBL13602652 0.75 CXCR4 (0.43) KDM4ECXCR4CXCL12GNAI3GNAO1
SCHEMBL6059264 0.73 RAD52 (0.39) KDM4ECXCR4CXCL12RAD52ALDH1A1
SCHEMBL10604006 0.72 CXCR4 (0.53) KDM4ECXCR4CXCL12GNAI3GNAO1
SCHEMBL4786588 0.72 CXCR4 (0.53) KDM4ECXCR4CXCL12GNAI3GNAO1
SCHEMBL4786617 0.72 CXCR4 (0.53) KDM4ECXCR4CXCL12GNAI3GNAO1
SCHEMBL4739261 0.72 CXCR4 (0.53) KDM4ECXCR4CXCL12GNAI3GNAO1
SCHEMBL841438 0.72 CXCR4 (0.53) KDM4ECXCR4CXCL12GNAI3GNAO1
SCHEMBL6645421 0.72 LMNA (0.51) KDM4ECXCR4CXCL12HRH4HRH3
SCHEMBL11520861 0.72 CXCR4 (0.52) KDM4ECXCR4CXCL12GNAI3GNAO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP claimed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US claimed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US claimed
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP disclosed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US disclosed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US disclosed