SCHEMBL7302738

SCHEMBL7302738

O=C(C1CCc2ccccc2C1)C1CCN[C@H]1C(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
F2 P00734 1/20 0.45
ACE P12821 3/20 0.41
PREP P48147 10/20 0.41
ALDH1A1 P00352 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CHRM2 P08172 1/20 0.40
CHRM4 P08173 1/20 0.40
CHRM1 P11229 1/20 0.40
CHRM3 P20309 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9048922 0.84 PREP (0.52) PREP
SCHEMBL9049902 0.84 F2 (0.48) F2ACEPREP
SCHEMBL9048049 0.84 F2 (0.48) F2ACEPREP
SCHEMBL9048078 0.84 PREP (0.52) PREP
SCHEMBL7300737 0.84 PREP (0.45) F2PREPCHRM2CHRM4CHRM1
SCHEMBL9171249 0.82 F2 (0.36) F2PREP
SCHEMBL7295630 0.82 F2 (0.60) F2ACEPREPALDH1A1SMN1; SMN2
SCHEMBL7302732 0.81 F2 (0.43) F2ACEPREPALDH1A1SMN1; SMN2
SCHEMBL7294365 0.79 PREP (0.48) PREP
SCHEMBL7294364 0.78 F2 (0.56) F2ACEPREPALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0372484-B1 Condensed benzene derivative ZERIA PHARM CO LTD (JP) 1994-10-26 EP disclosed
US-5028604-A Cognition Activators ZERIA PHARMACEUTICAL CO., LTD. (JP) 1991-07-02 US disclosed
EP-0372484-A2 Condensed benzene derivative ZERIA PHARMACEUTICAL CO., LTD. (JP) 1990-06-13 EP disclosed