SCHEMBL7294365

SCHEMBL7294365

O=C(C1CCc2ccccc2C1)C1CCN[C@H]1C(=O)N1CCSC1

nearest known ligand 0.48

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PREP P48147 8/20 0.48
DPP4 P27487 9/20 0.45
FAP Q12884 1/20 0.45
DPP8 Q6V1X1 2/20 0.42
DPP9 Q86TI2 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7300737 0.86 PREP (0.45) PREPDPP4FAP
SCHEMBL8155765 0.83 PREP (0.60) PREPDPP4FAPDPP8DPP9
SCHEMBL8154287 0.83 PREP (0.60) PREPDPP4FAPDPP8DPP9
SCHEMBL7295946 0.83 PREP (0.60) PREPDPP4FAPDPP8DPP9
SCHEMBL7305077 0.81 PREP (0.53) PREPDPP4FAPDPP8DPP9
SCHEMBL7294362 0.81 PREP (0.46) PREPDPP4FAPDPP8DPP9
SCHEMBL7302738 0.79 F2 (0.45) PREP
SCHEMBL9049641 0.78 PREP (0.44) PREPDPP4FAPDPP8
SCHEMBL9045362 0.78 PREP (0.44) PREPDPP4FAPDPP8
SCHEMBL7300891 0.77 PREP (0.48) PREPDPP4FAPDPP8DPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0372484-B1 Condensed benzene derivative ZERIA PHARM CO LTD (JP) 1994-10-26 EP disclosed
US-5028604-A Cognition Activators ZERIA PHARMACEUTICAL CO., LTD. (JP) 1991-07-02 US disclosed
EP-0372484-A2 Condensed benzene derivative ZERIA PHARMACEUTICAL CO., LTD. (JP) 1990-06-13 EP disclosed