Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 4/20 | 0.71 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.71 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.71 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 4/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29397805 | 0.83 | HTR4 (1.00) | HTR4NPSR1CYP1A2CYP2C9ALOX15 | |
| SCHEMBL1502039 | 0.83 | HTR4 (1.00) | HTR4NPSR1CYP1A2CYP2C9ALOX15 | |
| Maleic Acid SCHEMBL2942174 | 0.79 | HTR4 (0.90) | HTR4NPSR1CYP1A2CYP2C9ALOX15 | |
| SCHEMBL29626583 | 0.78 | HTR4 (1.00) | HTR4NPSR1CYP1A2CYP2C9ALOX15 | |
| SCHEMBL7293994 | 0.78 | HTR4 (0.89) | HTR4NPSR1CYP1A2CYP2C9ALOX15 | |
| SCHEMBL9703208 | 0.74 | HTR4 (0.61) | HTR4NPSR1CYP1A2CYP2C9ALOX15 | |
| Maleic Acid SCHEMBL7295111 | 0.74 | HTR4 (0.81) | HTR4NPSR1CYP1A2CYP2C9ALOX15 | |
| Fumaric Acid SCHEMBL7295114 | 0.74 | HTR4 (0.81) | HTR4NPSR1CYP1A2CYP2C9ALOX15 | |
| SCHEMBL7358522 | 0.74 | HTR4 (0.60) | HTR4NPSR1CYP1A2CYP2C9ALOX15 | |
| SCHEMBL598453 | 0.73 | HTR4 (0.55) | HTR4NPSR1CYP1A2CYP2C9ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0501322-B1 | 3-Piperidinylmethylcarboxylate substituted indoles | GLAXO GROUP LTD (GB) | 1996-09-04 | — | — | EP | claimed |