Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | CCR3 | P51677 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | HTR2A | P28223 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9616856 | 0.85 | HTR2A (0.63) | LMNASMN1; SMN2CCR3CYP1A2CYP3A4 | |
| SCHEMBL5757156 | 0.83 | HTR2A (0.69) | LMNASMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10712804 | 0.82 | HTR2A (0.66) | LMNASMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL227314 | 0.82 | TP53 (0.64) | LMNASMN1; SMN2CCR3CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL10715815 | 0.81 | HTR2A (0.64) | LMNASMN1; SMN2HTTHTR2A | |
| SCHEMBL14318600 | 0.79 | HTR2A (0.81) | LMNASMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11191382 | 0.79 | HTR2A (0.67) | CCR3CYP1A2CYP3A4CYP2D6KDM4E | |
| SCHEMBL227492 | 0.78 | MAPT (0.67) | LMNASMN1; SMN2CCR3CYP1A2CYP2C9 | |
| SCHEMBL11011779 | 0.78 | HSD11B1 (0.62) | CYP1A2CYP3A4CYP2D6KDM4EHTR2A | |
| SCHEMBL6300904 | 0.78 | CCR3 (0.62) | LMNACCR3HTR2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5229400-A | Cardiovascular disorders | AJINOMOTO CO., INC. (JP) | 1993-07-20 | — | — | US | disclosed |
| EP-0479601-A2 | Piperidine derivatives and their use as antiarrhythmic agents | Ajinomoto Co., Inc. (JP) | 1992-04-08 | — | — | EP | disclosed |