SCHEMBL7303012

SCHEMBL7303012

CCON1CCC(=C2c3ccccc3CSc3ccccc32)CC1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FNTA P49354 1/20 0.52
FNTB P49356 1/20 0.52
SETD7 Q8WTS6 6/20 0.48
CHRM2 P08172 5/20 0.48
ADRA2A P08913 5/20 0.48
CHRM1 P11229 5/20 0.48
ADRA1A P35348 5/20 0.48
DRD3 P35462 5/20 0.48
KCNH2 Q12809 5/20 0.48
SLC6A2 P23975 4/20 0.48
SLC6A4 P31645 4/20 0.48
SLC6A3 Q01959 4/20 0.48
DRD1 P21728 4/20 0.48
CYP2D6 P10635 4/20 0.48
HTR1A P08908 3/20 0.48
CYP2C19 P33261 3/20 0.48
TBXA2R P21731 2/20 0.48
OPRM1 P35372 2/20 0.48
ADORA3 P0DMS8 1/20 0.48
HTT P42858 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7297067 0.83 CHRM2 (0.69) FNTAFNTBSETD7CHRM2ADRA2A
SCHEMBL9844289 0.81 FNTA (0.61) FNTAFNTBSETD7CHRM2ADRA2A
SCHEMBL7674794 0.79 FNTA (0.55) FNTAFNTBSETD7CHRM2ADRA2A
SCHEMBL7676741 0.78 FNTA (0.53) FNTAFNTBSETD7CHRM2ADRA2A
SCHEMBL7679490 0.77 FNTA (0.52) FNTAFNTBSETD7CHRM2ADRA2A
SCHEMBL7682654 0.75 FNTA (0.50) FNTAFNTBSETD7CHRM2ADRA2A
SCHEMBL12854667 0.74 FNTA (0.59) FNTAFNTBSETD7CHRM2ADRA2A
SCHEMBL7679131 0.74 FNTA (0.59) FNTAFNTBSETD7CHRM2ADRA2A
SCHEMBL7682349 0.74 FNTA (0.53) FNTAFNTBSETD7CHRM2ADRA2A
SCHEMBL11599742 0.74 FNTA (0.56) FNTAFNTBSETD7CHRM2ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0530016-B1 Piperidine derivative and pharmaceutical composition containing it AJINOMOTO KK (JP) 1995-08-02 EP disclosed
EP-0530016-A2 Piperidine derivative and pharmaceutical composition containing it Ajinomoto Co., Inc. (JP) 1993-03-03 EP disclosed