Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 3/20 | 0.61 |
| ▸ | FNTB | P49356 | 3/20 | 0.61 |
| ▸ | HRH1 | P35367 | 7/20 | 0.59 |
| ▸ | PTAFR | P25105 | 1/20 | 0.50 |
| ▸ | SLC6A15 | Q9H2J7 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13870604 | 0.89 | HRH1 (0.50) | FNTAFNTBHRH1PTAFRSLC6A15 | |
| SCHEMBL7676741 | 0.86 | FNTA (0.53) | FNTAFNTBHRH1PTAFRSLC6A15 | |
| SCHEMBL12854667 | 0.86 | FNTA (0.59) | FNTAFNTBHRH1PTAFRSLC6A15 | |
| SCHEMBL9844364 | 0.86 | CHRM2 (0.57) | HRH1PTAFRSLC6A15LMNACYP3A4 | |
| SCHEMBL9850494 | 0.85 | HRH1 (0.76) | FNTAFNTBHRH1PTAFRSLC6A15 | |
| SCHEMBL7679490 | 0.84 | FNTA (0.52) | FNTAFNTBHRH1PTAFRLMNA | |
| SCHEMBL7682654 | 0.82 | FNTA (0.50) | FNTAFNTBHRH1PTAFRLMNA | |
| SCHEMBL9631337 | 0.81 | HRH1 (0.62) | HRH1PTAFRSLC6A15LMNACYP3A4 | |
| SCHEMBL7303012 | 0.81 | FNTA (0.52) | FNTAFNTBHRH1PTAFRLMNA | |
| SCHEMBL9718766 | 0.79 | HRH1 (0.61) | FNTAFNTBHRH1PTAFRSLC6A15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451772-A1 | Piperidine compounds, method for preparation thereof, and a pharamceutical composition comprising the same | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1991-10-16 | — | — | EP | disclosed |