SCHEMBL7303041

SCHEMBL7303041

COC(=O)[C@@H]1CCCN1C(=O)CC1Cc2ccc(Cl)cc2C1

nearest known ligand 0.58

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.58
PREP P48147 11/20 0.52
CPT2 P23786 1/20 0.43
CPT1A P50416 1/20 0.43
LMNA P02545 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ENPP2 Q13822 1/20 0.41
KLK5 Q9Y337 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7298194 0.87 PREP (0.52) ALDH1A1PREP
SCHEMBL7302927 0.86 PREP (0.68) ALDH1A1PREPKLK5
SCHEMBL7294184 0.82 PREP (0.69) PREPKLK5
SCHEMBL7296815 0.81 PREP (0.70) PREPKLK5
SCHEMBL7292882 0.81 PREP (0.70) PREPKLK5
SCHEMBL7294917 0.81 PREP (0.70) PREPKLK5
SCHEMBL7294906 0.81 PREP (0.70) PREPKLK5
SCHEMBL7301989 0.80 PREP (0.47) ALDH1A1PREPLMNARAB9ASMN1; SMN2
SCHEMBL7301169 0.80 PREP (0.70) PREP
SCHEMBL7299353 0.80 PREP (0.54) ALDH1A1PREP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0372484-B1 Condensed benzene derivative ZERIA PHARM CO LTD (JP) 1994-10-26 EP disclosed
US-5028604-A Cognition Activators ZERIA PHARMACEUTICAL CO., LTD. (JP) 1991-07-02 US disclosed
EP-0372484-A2 Condensed benzene derivative ZERIA PHARMACEUTICAL CO., LTD. (JP) 1990-06-13 EP disclosed