Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 11/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7302927 | 0.82 | PREP (0.68) | PREPALDH1A1KLK5ACE | |
| SCHEMBL7303041 | 0.80 | ALDH1A1 (0.58) | PREPALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL7298194 | 0.80 | PREP (0.52) | PREPALDH1A1 | |
| SCHEMBL7304087 | 0.79 | PREP (0.46) | PREPALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL7294184 | 0.78 | PREP (0.69) | PREPKLK5ACE | |
| SCHEMBL7293995 | 0.77 | PREP (0.47) | PREPALDH1A1ACE | |
| SCHEMBL7292882 | 0.76 | PREP (0.70) | PREPKLK5ACE | |
| SCHEMBL7294906 | 0.76 | PREP (0.70) | PREPKLK5ACE | |
| SCHEMBL7296815 | 0.76 | PREP (0.70) | PREPKLK5ACE | |
| SCHEMBL7294917 | 0.76 | PREP (0.70) | PREPKLK5ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372484-B1 | Condensed benzene derivative | ZERIA PHARM CO LTD (JP) | 1994-10-26 | — | — | EP | disclosed |
| US-5028604-A | Cognition Activators | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0372484-A2 | Condensed benzene derivative | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1990-06-13 | — | — | EP | disclosed |