Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9057786 | 1.00 | POLB (0.32) | POLB | |
| SCHEMBL371756 | 1.00 | POLB (0.32) | POLB | |
| SCHEMBL372038 | 0.84 | POLB (0.37) | POLB | |
| SCHEMBL5937915 | 0.84 | POLB (0.37) | POLB | |
| SCHEMBL5937867 | 0.76 | POLB (0.36) | POLB | |
| Hydrochloric Acid SCHEMBL19741914 | 0.73 | CHRNB2 (0.37) | — | |
| SCHEMBL5939234 | 0.71 | — | — | |
| SCHEMBL5939229 | 0.71 | — | — | |
| SCHEMBL371918 | 0.71 | ATM (0.32) | — | |
| SCHEMBL2115150 | 0.71 | ATM (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0454121-B1 | Azatetracyclic compounds | SEARLE & CO (US) | 1996-11-13 | — | — | EP | claimed |
| US-5223613-A | Prepared from cyclopenta(c)pyrrole derivatives; drug intermediates; antiemetics, anixiolytics | G. D. SEARLE & CO. (US) | 1993-06-29 | — | — | US | claimed |
| EP-0454121-A2 | Azatetracyclic compounds | G.D. Searle & Co. (US) | 1991-10-30 | — | — | EP | claimed |
| US-5650535-A | FORMING NORBORNENE BY CHEMICAL CONDENSATION OF UNSATURATED ESTER WITH CYCLOPENTADIENE IN TRIETHYLAMINE | G. D. SEARLE & CO. (US) | 1997-07-22 | — | — | US | disclosed |
| EP-0454121-B1 | Azatetracyclic compounds | SEARLE & CO (US) | 1996-11-13 | — | — | EP | disclosed |
| US-5541344-A | 5-HT AGONISTS, ANTAGONISTS, IODINATED TRICYLIC LACTONES | G. D. SEARLE & CO. (US) | 1996-07-30 | — | — | US | disclosed |
| US-5223613-A | Prepared from cyclopenta(c)pyrrole derivatives; drug intermediates; antiemetics, anixiolytics | G. D. SEARLE & CO. (US) | 1993-06-29 | — | — | US | disclosed |
| US-5140023-A | Serontonin antagonist; gastrointestinal and psychological disorders; analgesics; antidepressants | G. D. SEARLE & CO. (US) | 1992-08-18 | — | — | US | disclosed |
| EP-0454121-A2 | Azatetracyclic compounds | G.D. Searle & Co. (US) | 1991-10-30 | — | — | EP | disclosed |