Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.67 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.67 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.51 |
| ▸ | PLAU | P00749 | 2/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | PLAT | P00750 | 1/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310729 | 0.94 | ITGB3 (0.77) | ITGB3ITGA2BDGAT1MCHR1 | |
| SCHEMBL7298855 | 0.87 | ITGB3 (0.88) | ITGB3ITGA2BDGAT1PLAU | |
| SCHEMBL7306072 | 0.87 | ITGB3 (0.77) | ITGB3ITGA2BDGAT1MCHR1 | |
| SCHEMBL7305638 | 0.82 | ITGB3 (0.55) | ITGB3ITGA2BDGAT1MCHR1 | |
| SCHEMBL7300021 | 0.82 | ITGB3 (0.86) | ITGB3ITGA2BDGAT1MCHR1 | |
| SCHEMBL7298489 | 0.80 | ITGB3 (1.00) | ITGB3ITGA2BPLAUMCHR1 | |
| SCHEMBL7298689 | 0.80 | ITGB3 (0.58) | ITGB3ITGA2BMCHR1 | |
| SCHEMBL7396140 | 0.80 | ITGB3 (0.74) | ITGB3ITGA2BDGAT1MCHR1 | |
| Hydrochloric Acid SCHEMBL7309818 | 0.80 | ITGB3 (0.98) | ITGB3ITGA2BPLAUMCHR1 | |
| SCHEMBL7444354 | 0.79 | ITGB3 (0.73) | ITGB3ITGA2BDGAT1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709370-B1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5629321-A | FIBRINOGEN ANTAGONIST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | disclosed |