Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 9/20 | 0.60 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7308386 | 0.98 | METAP2 (0.59) | METAP2EPHX1ALDH1A1NPSR1METAP1 | |
| SCHEMBL21118051 | 0.79 | METAP2 (0.47) | METAP2ALDH1A1NPSR1TSHR | |
| SCHEMBL9555738 | 0.79 | METAP2 (0.47) | METAP2ALDH1A1NPSR1TSHR | |
| SCHEMBL13836892 | 0.79 | METAP2 (0.47) | METAP2ALDH1A1NPSR1TSHR | |
| SCHEMBL6304330 | 0.78 | METAP2 (0.45) | METAP2ALDH1A1METAP1LMNATSHR | |
| Hydrochloric Acid SCHEMBL9555735 | 0.78 | METAP2 (0.46) | METAP2ALDH1A1NPSR1TSHR | |
| Hydrochloric Acid SCHEMBL9710402 | 0.78 | METAP2 (0.46) | METAP2ALDH1A1NPSR1TSHR | |
| SCHEMBL20543740 | 0.77 | METAP2 (0.45) | METAP2ALDH1A1NPSR1LMNATSHR | |
| SCHEMBL3620878 | 0.76 | METAP2 (0.58) | METAP2EPHX1ALDH1A1NPSR1METAP1 | |
| Hydrochloric Acid SCHEMBL13585571 | 0.76 | METAP2 (0.42) | METAP2ALDH1A1METAP1CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520336-A2 | Aldehyde derivatives and their use as calpain inhibitors | FUJIREBIO Inc. (JP) | 1992-12-30 | — | — | EP | disclosed |