Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 9/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 5/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28256389 | 0.87 | ACE (0.60) | ACEKMT2AL3MBTL1LTA4HACE2 | |
| SCHEMBL30052918 | 0.87 | ACE (0.60) | ACEKMT2AL3MBTL1LTA4HACE2 | |
| SCHEMBL10766372 | 0.84 | ACE (0.60) | ACELTA4HACE2 | |
| SCHEMBL9069203 | 0.84 | ACE (0.60) | ACELTA4HACE2 | |
| SCHEMBL9068758 | 0.84 | ACE (0.60) | ACELTA4HACE2 | |
| SCHEMBL9090988 | 0.84 | ACE (0.60) | ACELTA4HACE2 | |
| SCHEMBL9069201 | 0.84 | ACE (0.60) | ACELTA4HACE2 | |
| SCHEMBL9068759 | 0.84 | ACE (0.60) | ACELTA4HACE2 | |
| SCHEMBL15251739 | 0.81 | KMT2A (0.59) | ACEKMT2AL3MBTL1LTA4HACE2 | |
| SCHEMBL15251740 | 0.81 | KMT2A (0.59) | ACEKMT2AL3MBTL1LTA4HACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0595878-A1 | ACYLMERCAPTOALKANOYLDIPEPTIDES, METHODS OF PREPARATION AND THEIR THERAPEUTIC USE | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1994-05-11 | — | — | EP | claimed |
| WO-1993002099-A1 | ACYLMERCAPTOALKANOYLDIPEPTIDES, METHODS OF PREPARATION AND THEIR THERAPEUTIC USE | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1993-02-04 | — | — | WO | claimed |
| EP-0524553-A1 | Acylmercaptoalkanoyldipeptides, methods of preparation and their therapeutic use | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1993-01-27 | — | — | EP | claimed |
| US-5801274-A | N- mercaptoacyl(amino acid or peptide)! compounds and S-lipophilic aliphatic carbonyl derivatives thereof as antihypertensives | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1998-09-01 | — | — | US | disclosed |
| US-5591891-A | PEPTIDASE INHIBITORS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1997-01-07 | — | — | US | disclosed |
| WO-1994017036-A1 | S-LIPOPHILIC ALIPHATIC CARBONYL [N-MERCAPTOACYL-(AMINO ACID OR PEPTIDE)] COMPOUNDS AS ANTIHYPERTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1994-08-04 | — | — | WO | disclosed |