Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 12/20 | 0.60 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.56 |
| ▸ | LTA4H | P09960 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10766372 | 1.00 | ACE (0.60) | ACEACE2LTA4HLMNA | |
| SCHEMBL9069203 | 1.00 | ACE (0.60) | ACEACE2LTA4HLMNA | |
| SCHEMBL9068759 | 1.00 | ACE (0.60) | ACEACE2LTA4HLMNA | |
| SCHEMBL9090988 | 1.00 | ACE (0.60) | ACEACE2LTA4HLMNA | |
| SCHEMBL9069201 | 1.00 | ACE (0.60) | ACEACE2LTA4HLMNA | |
| SCHEMBL10765228 | 0.96 | ACE (0.56) | ACEACE2LTA4HLMNA | |
| SCHEMBL10764673 | 0.89 | ACE (0.68) | ACEACE2LMNA | |
| SCHEMBL10764668 | 0.89 | ACE (0.68) | ACEACE2LMNA | |
| SCHEMBL10766006 | 0.88 | ACE (0.57) | ACEACE2 | |
| SCHEMBL7315965 | 0.87 | ACE (0.63) | ACEACE2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0174571-A2 | Derivatives of amino acids, process for their preparation and pharmaceutical compositions | BOEHRINGER INGELHEIM KG (DE) | 1986-03-19 | — | — | EP | claimed |
| US-5496805-A | DIURETIC, HYPOTENSIVE | E. R. SQUIBB & SONS, INC. (US) | 1996-03-05 | — | — | US | disclosed |
| EP-0230922-A2 | Use of peptides in the preparation of agents for the treatment of coronary diseases or organic brain syndrome | BOEHRINGER INGELHEIM KG (DE) | 1987-08-05 | — | — | EP | disclosed |
| EP-0174571-A2 | Derivatives of amino acids, process for their preparation and pharmaceutical compositions | BOEHRINGER INGELHEIM KG (DE) | 1986-03-19 | — | — | EP | disclosed |