Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | SLC1A5 | Q15758 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11868080 | 0.85 | SMN1; SMN2 (0.50) | KMT2AMEN1SMN1; SMN2ALDH1A1SLC1A5 | |
| SCHEMBL7300113 | 0.85 | SMN1; SMN2 (0.50) | KMT2AMEN1SMN1; SMN2ALDH1A1SLC1A5 | |
| SCHEMBL31691522 | 0.83 | SLC1A5 (0.53) | SLC1A5 | |
| SCHEMBL22444963 | 0.83 | SLC1A5 (0.53) | SLC1A5 | |
| SCHEMBL16148359 | 0.83 | SLC1A5 (0.53) | SLC1A5 | |
| SCHEMBL16148360 | 0.83 | SLC1A5 (0.53) | SLC1A5 | |
| SCHEMBL11568937 | 0.82 | CYP1A2 (0.55) | SMN1; SMN2ALDH1A1SLC1A5MAPTHPGD | |
| SCHEMBL7303334 | 0.81 | KMT2A (0.46) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL341585 | 0.80 | CYP2C19 (0.61) | SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL2829691 | 0.80 | CYP2C19 (0.61) | SMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520336-A2 | Aldehyde derivatives and their use as calpain inhibitors | FUJIREBIO Inc. (JP) | 1992-12-30 | — | — | EP | disclosed |