Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 1/20 | 0.62 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.62 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.62 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.62 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.45 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310306 | 0.98 | S1PR2 (0.59) | S1PR2S1PR4S1PR1S1PR3MAOA | |
| SCHEMBL28779881 | 0.98 | S1PR2 (0.59) | S1PR2S1PR4S1PR1S1PR3MAOA | |
| SCHEMBL6820069 | 0.92 | S1PR2 (0.53) | S1PR2S1PR4S1PR1S1PR3MAOA | |
| SCHEMBL7309652 | 0.92 | S1PR2 (0.53) | S1PR2S1PR4S1PR1S1PR3MAOA | |
| SCHEMBL6820062 | 0.92 | S1PR2 (0.53) | S1PR2S1PR4S1PR1S1PR3MAOA | |
| SCHEMBL1177666 | 0.84 | ANPEP (0.53) | S1PR2S1PR4S1PR1S1PR3GRIK1 | |
| SCHEMBL4969986 | 0.84 | ANPEP (0.53) | S1PR2S1PR4S1PR1S1PR3GRIK1 | |
| SCHEMBL1568623 | 0.84 | ANPEP (0.53) | S1PR2S1PR4S1PR1S1PR3GRIK1 | |
| SCHEMBL11816141 | 0.83 | S1PR2 (0.59) | S1PR2S1PR4S1PR1S1PR3MAOA | |
| SCHEMBL5681630 | 0.81 | S1PR2 (0.58) | S1PR2S1PR4S1PR1S1PR3MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520336-A2 | Aldehyde derivatives and their use as calpain inhibitors | FUJIREBIO Inc. (JP) | 1992-12-30 | — | — | EP | disclosed |