Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CPA1 | P15085 | 2/20 | 0.48 |
| ▸ | CPB1 | P15086 | 1/20 | 0.48 |
| ▸ | CPA3 | P15088 | 1/20 | 0.48 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7288415 | 0.90 | MAPK1 (0.62) | ALDH1A1LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL7298841 | 0.78 | KMT2A (0.48) | ALDH1A1LMNACYP1A2CPA1CPB1 | |
| SCHEMBL14543840 | 0.78 | OPRL1 (0.66) | ALDH1A1TSHRTP53CYP1A2CYP3A4 | |
| SCHEMBL9554486 | 0.77 | CPA1 (0.60) | LMNATSHRCYP1A2CYP3A4CPA1 | |
| SCHEMBL9554490 | 0.77 | CPA1 (0.60) | LMNATSHRCYP1A2CYP3A4CPA1 | |
| SCHEMBL15109569 | 0.77 | HRH3 (0.65) | ALDH1A1LMNAACHETSHRCYP3A4 | |
| SCHEMBL7280897 | 0.77 | SMN1; SMN2 (0.61) | ALDH1A1LMNATSHRSMN1; SMN2 | |
| SCHEMBL2804430 | 0.76 | CPA1 (0.63) | LMNACYP1A2CPA1CPB1CPA3 | |
| SCHEMBL6248582 | 0.76 | TACR2 (0.65) | TSHRTP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10720789 | 0.74 | ALDH1A1 (1.00) | ALDH1A1MAPK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5063208-A | Cardiovascular disorders, vision defects | ABBOTT LABORATORIES (US) | 1991-11-05 | — | — | US | disclosed |
| EP-0410260-A2 | Peptidyl aminodiol renin inhibitors | ABBOTT LABORATORIES (US) | 1991-01-30 | — | — | EP | disclosed |