Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.62 |
| ▸ | PPARG | P37231 | 2/20 | 0.62 |
| ▸ | PPARA | Q07869 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 7/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | DHODH | Q02127 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | NPY1R | P25929 | 1/20 | 0.59 |
| ▸ | NPY2R | P49146 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14288429 | 0.92 | CYP1A2 (0.63) | NR1H4PPARGPPARAMAPTALDH1A1 | |
| SCHEMBL10605968 | 0.90 | GAA (0.66) | MAPTALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL7291782 | 0.89 | MAPT (0.62) | NR1H4PPARGPPARAMAPTALDH1A1 | |
| SCHEMBL28863360 | 0.86 | ALDH1A1 (0.62) | MAPTALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL29960935 | 0.86 | GAA (0.61) | MAPTALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL9335190 | 0.85 | GAA (0.59) | MAPTALDH1A1SMN1; SMN2HTTKDM4E | |
| SCHEMBL7295108 | 0.85 | TP53 (0.81) | NR1H4PPARGPPARAMAPTALDH1A1 | |
| SCHEMBL11506084 | 0.85 | HDAC1 (0.68) | MAPTALDH1A1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL15345364 | 0.84 | MAPT (0.65) | NR1H4PPARGPPARAMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL11414769 | 0.83 | HDAC1 (0.67) | MAPTALDH1A1SMN1; SMN2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358118-B1 | Phenylamides - process for their preparation as well as a drug containing those compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-5135949-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-04 | — | — | US | disclosed |
| EP-0358118-A1 | Phenylamides - process for their preparation as well as a drug containing those compounds | Roche Diagnostics GmbH (DE) | 1990-03-14 | — | — | EP | disclosed |