Acetamide

Acetamide

SCHEMBL7303967

CC(N)=O.CN1CCN(CS)C(Cc2ccccc2)C1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.50
CA2 P00918 4/20 0.50
CA4 P22748 4/20 0.50
CA9 Q16790 4/20 0.50
DPP4 P27487 1/20 0.46
ABCB1 P08183 1/20 0.43
SIGMAR1 Q99720 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2753534 0.79 CA1 (0.63) CA1CA2CA4CA9DPP4
SCHEMBL13859623 0.78 SIGMAR1 (0.54) CA1CA2CA4CA9SIGMAR1
SCHEMBL18081174 0.77 ABCB1 (0.62) CA1CA2CA4CA9DPP4
SCHEMBL12143610 0.77 ABCB1 (0.62) CA1CA2CA4CA9DPP4
SCHEMBL12143612 0.77 ABCB1 (0.62) CA1CA2CA4CA9DPP4
SCHEMBL2538770 0.75 CA1 (0.62) CA1CA2CA4CA9DPP4
SCHEMBL8918158 0.73 CA1 (0.49) CA1CA2CA4CA9DPP4
SCHEMBL6244506 0.71 MC4R (0.49) CA1CA2CA4CA9DPP4
SCHEMBL25154734 0.70 SIGMAR1 (0.59) CA1CA2CA4CA9SIGMAR1
SCHEMBL19468375 0.70 CA1 (0.54) CA1CA2CA4CA9DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0465369-B1 N-substituted derivatives of alpha-mercapto alkylamines, process for their preparation and intermediates obtained, their use as medicaments and compositions containing them ROUSSEL UCLAF (FR) 1994-04-13 EP disclosed
EP-0465369-A1 N-substituted derivatives of alpha-mercapto alkylamines, process for their preparation and intermediates obtained, their use as medicaments and compositions containing them ROUSSEL-UCLAF (FR) 1992-01-08 EP disclosed