Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 11/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7305842 | 0.93 | F2 (0.37) | F2 | |
| SCHEMBL9283351 | 0.84 | F2 (0.35) | F2ALDH1A1 | |
| SCHEMBL7298314 | 0.82 | F2 (0.42) | F2HPGD | |
| SCHEMBL8947611 | 0.80 | CA12 (0.36) | F2LMNAHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL7304125 | 0.80 | CA12 (0.36) | F2LMNAHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL7293781 | 0.80 | F2 (0.46) | F2L3MBTL1ALDH1A1 | |
| SCHEMBL8947624 | 0.79 | F2 (0.44) | F2L3MBTL1ALDH1A1 | |
| SCHEMBL7294941 | 0.79 | F2 (0.34) | F2 | |
| SCHEMBL7299072 | 0.78 | F2 (0.38) | F2 | |
| SCHEMBL9164171 | 0.78 | F2 (0.54) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559046-A1 | N-amidinopiperidinyl(3/4)- or N-amidino-1,4-Oxazinyl(2)-substituted sulfonamides, process for their preparation and use as thrombin inhibitors | F.HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT (CH) | 1993-09-08 | — | — | EP | disclosed |