Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.36 |
| ▸ | CA9 | Q16790 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7304125 | 1.00 | CA12 (0.36) | CA12CA9ALDH1A1CA1CA2 | |
| SCHEMBL7296038 | 0.84 | CYP1A2 (0.31) | CA12CA1 | |
| SCHEMBL27380499 | 0.84 | CYP1A2 (0.31) | CA12CA1 | |
| SCHEMBL7303910 | 0.84 | ACACB (0.43) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7301032 | 0.82 | TSHR (0.36) | HSD17B10F2ITGB3ITGA2B | |
| SCHEMBL7298351 | 0.81 | F2 (0.43) | ALDH1A1MMP2MMP9MMP13SMN1; SMN2 | |
| SCHEMBL7303719 | 0.81 | EEF2K (0.36) | MMP1MMP2MMP9MMP13HSD17B10 | |
| SCHEMBL7295250 | 0.80 | L3MBTL1 (0.39) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL7303979 | 0.80 | F2 (0.40) | ALDH1A1SMN1; SMN2LMNAHPGDF2 | |
| SCHEMBL7338481 | 0.80 | F2 (0.43) | F2ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578594-A | ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1996-11-26 | — | — | US | disclosed |
| US-5405854-A | Anticoagulants | HOFFMANN-LA ROCHE INC. (US) | 1995-04-11 | — | — | US | disclosed |