Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.69 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.69 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.69 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.69 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9694595 | 1.00 | HDAC3 (0.69) | HDAC3HDAC11HDAC8HDAC6TRPV1 | |
| Hydrochloric Acid SCHEMBL7713301 | 0.88 | MAPT (0.71) | HDAC6RAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL7303163 | 0.88 | HDAC3 (0.86) | HDAC3HDAC11HDAC8HDAC6TRPV1 | |
| SCHEMBL15149489 | 0.86 | CNR2 (0.53) | HDAC3HDAC11HDAC8HDAC6TRPV1 | |
| SCHEMBL2342357 | 0.86 | SIRT1 (0.68) | HDAC3HDAC11HDAC8HDAC6RAB9A | |
| SCHEMBL8770238 | 0.85 | MAPT (0.68) | HDAC6RAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL1663761 | 0.85 | MAPT (0.68) | RAB9ANPC1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL30828562 | 0.85 | HDAC1 (0.69) | HDAC6RAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL1664367 | 0.85 | MAPT (0.68) | HDAC6RAB9ANPC1SMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL2353336 | 0.84 | SIRT1 (0.67) | HDAC3HDAC11HDAC8HDAC6RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358118-B1 | Phenylamides - process for their preparation as well as a drug containing those compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-5135949-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-04 | — | — | US | disclosed |