Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PADI4 | Q9UM07 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | IDE | P14735 | 1/20 | 0.40 |
| ▸ | MPI | P34949 | 1/20 | 0.40 |
| ▸ | S100A4 | P26447 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27740 | 0.83 | IDO1 (0.53) | PADI4HSP90AA1KDM4EMAPTALDH1A1 | |
| SCHEMBL29648165 | 0.83 | IDO1 (0.53) | PADI4HSP90AA1KDM4EMAPTALDH1A1 | |
| SCHEMBL30503415 | 0.76 | PADI4 (0.55) | PADI4HSP90AA1KDM4EMAPTALDH1A1 | |
| SCHEMBL888293 | 0.76 | PADI4 (0.55) | PADI4HSP90AA1KDM4EMAPTALDH1A1 | |
| Formaldehyde SCHEMBL11154820 | 0.75 | PADI4 (0.54) | PADI4HSP90AA1KDM4EMAPTALDH1A1 | |
| Acetic Acid SCHEMBL11780463 | 0.74 | KDM4E (0.52) | PADI4HSP90AA1KDM4EMAPTALDH1A1 | |
| SCHEMBL819204 | 0.74 | ALDH1A1 (0.45) | PADI4HSP90AA1KDM4EMAPTALDH1A1 | |
| Anthraquinone SCHEMBL1376042 | 0.73 | ALDH1A1 (0.41) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL526630 | 0.73 | IDO1 (0.56) | PADI4HSP90AA1KDM4EMAPTALDH1A1 | |
| SCHEMBL18068454 | 0.72 | KDM4E (0.46) | PADI4HSP90AA1KDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629406-A | AMINO ACID DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0587311-A1 | Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |