Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.47 |
| ▸ | HTR7 | P34969 | 2/20 | 0.46 |
| ▸ | METAP1 | P53582 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9426279 | 0.99 | METAP1 (0.47) | ACHEHTR7METAP1SIGMAR1CYP19A1 | |
| SCHEMBL7314737 | 0.95 | ACHE (0.49) | ACHEHTR7METAP1SIGMAR1CYP19A1 | |
| SCHEMBL7303893 | 0.94 | CYP19A1 (0.49) | ACHEMETAP1SIGMAR1CYP19A1HTR2C | |
| Hydrochloric Acid SCHEMBL9426039 | 0.94 | METAP1 (0.49) | ACHEHTR7METAP1SIGMAR1CYP19A1 | |
| Hydrochloric Acid SCHEMBL9425569 | 0.93 | CYP19A1 (0.48) | ACHEMETAP1SIGMAR1CYP19A1HTR2C | |
| SCHEMBL7303491 | 0.90 | CYP19A1 (0.50) | ACHEMETAP1SIGMAR1CYP19A1HTR2C | |
| Hydrochloric Acid SCHEMBL9426786 | 0.89 | CYP19A1 (0.49) | ACHEMETAP1SIGMAR1CYP19A1HTR2C | |
| SCHEMBL7302478 | 0.87 | CYP19A1 (0.52) | ACHEMETAP1SIGMAR1CYP19A1HTR2C | |
| Hydrochloric Acid SCHEMBL9425589 | 0.86 | METAP1 (0.51) | ACHEHTR7METAP1SIGMAR1CYP19A1 | |
| SCHEMBL7307617 | 0.81 | ACHE (0.46) | ACHEHTR7METAP1SIGMAR1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581677-B1 | Cycloalkylalkylamines which are sigma-receptor ligands, process for preparing them and their application in therapy | JOUVEINAL INST RECH (FR) | 1997-01-08 | — | — | EP | disclosed |
| US-5326784-A | Psychological and gastrointestinal disorders | INSTITUT DE RECHERCHE JOUVEINAL (FR) | 1994-07-05 | — | — | US | disclosed |
| EP-0581677-A1 | Cycloalkylalkylamines which are sigma-receptor ligands, process for preparing them and their application in therapy | INSTITUT DE RECHERCHE JOUVEINAL (I.R.J) (FR) | 1994-02-02 | — | — | EP | disclosed |