Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.61 |
| ▸ | CA2 | P00918 | 4/20 | 0.61 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | STK10 | O94804 | 1/20 | 0.38 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL819485 | 0.79 | CA1 (0.56) | CA1CA2XDHSLC22A12TSHR | |
| SCHEMBL29482237 | 0.79 | CA1 (0.56) | CA1CA2XDHSLC22A12TSHR | |
| SCHEMBL4655972 | 0.79 | CA1 (0.56) | CA1CA2XDHSLC22A12TSHR | |
| SCHEMBL2186565 | 0.78 | CA1 (0.55) | CA1CA2XDHSLC22A12TSHR | |
| SCHEMBL4078176 | 0.78 | CA1 (0.55) | CA1CA2XDHSLC22A12TSHR | |
| SCHEMBL23087600 | 0.78 | CA1 (0.59) | CA1CA2XDHSLC22A12TSHR | |
| SCHEMBL2641520 | 0.78 | CA1 (0.55) | CA1CA2XDHSLC22A12TSHR | |
| SCHEMBL2185041 | 0.78 | NQO2 (0.55) | CA1CA2XDHSLC22A12TSHR | |
| SCHEMBL3970625 | 0.78 | CYP1A2 (0.55) | CA1CA2XDHSLC22A12TSHR | |
| SCHEMBL27002350 | 0.78 | CA1 (0.55) | CA1CA2XDHSLC22A12TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629406-A | AMINO ACID DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0587311-A1 | Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |