Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | HRH2 | P25021 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7311470 | 0.98 | POLB (0.41) | POLBSMN1; SMN2CXCR4SIGMAR1HRH2 | |
| SCHEMBL24764732 | 0.96 | MEN1 (0.41) | POLBSMN1; SMN2CXCR4SIGMAR1HRH2 | |
| SCHEMBL20366241 | 0.96 | MEN1 (0.41) | POLBSMN1; SMN2CXCR4SIGMAR1HRH2 | |
| SCHEMBL22128496 | 0.96 | MEN1 (0.41) | POLBSMN1; SMN2CXCR4SIGMAR1HRH2 | |
| Trifluoroacetic Acid SCHEMBL31732071 | 0.83 | MEN1 (0.44) | SMN1; SMN2SIGMAR1MEN1KMT2AKDM4E | |
| SCHEMBL5322116 | 0.82 | HRH3 (0.41) | SMN1; SMN2HRH3LTA4HKDM4EALDH1A1 | |
| SCHEMBL23987984 | 0.81 | CXCR4 (0.52) | POLBSMN1; SMN2CXCR4SIGMAR1HRH2 | |
| SCHEMBL7604054 | 0.81 | POLB (0.57) | POLBSMN1; SMN2CXCR4SIGMAR1HRH2 | |
| SCHEMBL5327291 | 0.80 | HRH3 (0.44) | HRH3LTA4H | |
| Iodide SCHEMBL7948152 | 0.79 | POLB (0.55) | POLBSMN1; SMN2CXCR4SIGMAR1HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015106294-A1 | BIVALENT BCR-ABL TYROSINE KINASE LIGANDS, AND METHODS OF USING SAME | COFERON,INC. (US) | 2015-07-16 | — | — | WO | disclosed |
| EP-0839805-B1 | Pyrrolidinone derivatives and their use as antipsychotic medicaments | SCHERING AG (DE) | 2001-10-04 | — | — | EP | disclosed |
| US-5969138-A | ANTIPSYCHOTIC AGENTS | MITSUI CHEMICALS, INC. (JP) | 1999-10-19 | — | — | US | disclosed |
| EP-0839805-A1 | Pyrrolidinone derivatives and their use as antipsychotic medicaments | MITSUI TOATSU CHEMICALS, INC. (JP) | 1998-05-06 | — | — | EP | disclosed |