SCHEMBL20366241

SCHEMBL20366241

C#CCOCCOCCOCCOCCN1CCNCC1

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
POLB P06746 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CXCR4 P61073 2/20 0.39
SIGMAR1 Q99720 3/20 0.37
HRH2 P25021 2/20 0.37
HRH1 P35367 2/20 0.37
HRH3 Q9Y5N1 2/20 0.37
HTR2C P28335 2/20 0.36
LTA4H P09960 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24764732 1.00 MEN1 (0.41) MEN1KMT2APOLBSMN1; SMN2KDM4E
SCHEMBL22128496 1.00 MEN1 (0.41) MEN1KMT2APOLBSMN1; SMN2KDM4E
SCHEMBL7304959 0.96 POLB (0.42) MEN1KMT2APOLBSMN1; SMN2KDM4E
Hydrochloric Acid SCHEMBL7311470 0.95 POLB (0.41) MEN1KMT2APOLBSMN1; SMN2KDM4E
Trifluoroacetic Acid SCHEMBL31732071 0.86 MEN1 (0.44) MEN1KMT2ASMN1; SMN2KDM4EALDH1A1
SCHEMBL24533526 0.83 KDM4E (0.40) MEN1KMT2ASMN1; SMN2KDM4EALDH1A1
SCHEMBL23987984 0.82 CXCR4 (0.52) MEN1KMT2APOLBSMN1; SMN2KDM4E
SCHEMBL5322116 0.79 HRH3 (0.41) SMN1; SMN2KDM4EALDH1A1HRH3LTA4H
SCHEMBL23100650 0.79 KDM4E (0.36) MEN1KMT2ASMN1; SMN2KDM4EALDH1A1
SCHEMBL22788623 0.79 KDM4E (0.36) MEN1KMT2AKDM4EALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024010810-A2 FC CONJUGATES INCLUDING AN INHIBITOR OF CD73 AND USES THEREOF CIDARA THERAPEUTICS, INC. (US) 2024-01-11 WO disclosed
US-20230190950-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS CIDARA THERAPEUTICS, INC. 2023-06-22 US disclosed
US-20230165970-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS CIDARA THERAPEUTICS, INC. 2023-06-01 US disclosed
WO-2022133281-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF HUMAN IMMUNODEFICIENCY VIRUS CIDARA THERAPEUTICS, INC. (US) 2022-06-23 WO disclosed
WO-2018128826-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS CIDARA THERAPEUTICS, INC. (US) 2018-07-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230190950-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS FCGR3B, FCGR1A, FCGR2A MEN1 3001/4885KMT2A 4310/4885POLB 1639/4885
US-20230165970-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS FCGR3B, FCGR1A, FCGR2A MEN1 3001/4885KMT2A 4310/4885POLB 1639/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.