Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18716747 | 0.79 | SLC6A4 (0.40) | MAPTHSD17B10ALDH1A1NR2F2L3MBTL1 | |
| SCHEMBL7034976 | 0.77 | HPGD (0.43) | GAAALDH1A1 | |
| SCHEMBL358606 | 0.73 | PDCD1 (0.43) | HSD17B10ALDH1A1TRPA1ATM | |
| SCHEMBL7533571 | 0.72 | HPGD (0.40) | GAAALDH1A1 | |
| SCHEMBL9839922 | 0.72 | TAAR1 (0.34) | TRPA1ATM | |
| Phosphine SCHEMBL3840466 | 0.71 | PDCD1 (0.42) | TRPA1ATM | |
| Ammonia Solution, Strong SCHEMBL439692 | 0.71 | PDCD1 (0.42) | ALDH1A1TRPA1ATM | |
| SCHEMBL11227494 | 0.71 | CHRM2 (0.42) | TP53HSD17B10ALDH1A1 | |
| Hydrochloric Acid SCHEMBL22557689 | 0.71 | — | — | |
| SCHEMBL8436160 | 0.70 | CYP1A2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421366-B1 | Radiolabeled anticoagulant peptides | MERRELL DOW PHARMA (US) | 1995-07-19 | — | — | EP | disclosed |
| US-5279812-A | Polypeptide; amino acid sequence of hirudin | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-01-18 | — | — | US | disclosed |