Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 14/20 | 0.63 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 5/20 | 0.32 |
| ▸ | TPSD1 | Q9BZJ3 | 5/20 | 0.32 |
| ▸ | TPSG1 | Q9NRR2 | 5/20 | 0.32 |
| ▸ | PARL | Q9H300 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7304572 | 0.79 | ELANE (0.58) | ELANE | |
| SCHEMBL7297808 | 0.78 | ELANE (0.57) | ELANE | |
| SCHEMBL7438739 | 0.77 | ELANE (1.00) | ELANE | |
| SCHEMBL7306702 | 0.75 | ELANE (0.61) | ELANE | |
| Methyl Alcohol SCHEMBL7330929 | 0.72 | ELANE (0.60) | ELANETPSAB1TPSD1TPSG1 | |
| SCHEMBL7332156 | 0.72 | ELANE (0.59) | ELANETPSAB1TPSD1TPSG1PARL | |
| SCHEMBL7304995 | 0.67 | ELANE (0.52) | ELANE | |
| SCHEMBL7295634 | 0.65 | ELANE (0.44) | ELANE | |
| SCHEMBL7336876 | 0.65 | ELANE (0.51) | ELANETPSAB1TPSD1TPSG1PARL | |
| SCHEMBL28479582 | 0.64 | MEN1 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550111-B1 | 2-Saccharinylmethyl heterocyclic carboxylates useful as proteolytic enzyme inhibitors and pharmaceutical compositions containing them | SANOFI SA (FR) | 1999-04-14 | — | — | EP | disclosed |
| EP-0550111-A1 | 2-Saccharinylmethyl heterocyclic carboxylates useful as proteolytic enzyme inhibitors and pharmaceutical compositions containing them | STERLING WINTHROP INC. (US) | 1993-07-07 | — | — | EP | disclosed |