SCHEMBL7305053

SCHEMBL7305053

COc1ccc2c(c1)CC(CC(=O)N1CCC[C@@H]1C(=O)N1CCSC1)C2

nearest known ligand 0.73

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PREP P48147 18/20 0.73
DPP4 P27487 1/20 0.43
DPP8 Q6V1X1 1/20 0.43
DPP9 Q86TI2 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7305043 1.00 PREP (0.73) PREPDPP4DPP8DPP9
SCHEMBL7296561 0.95 PREP (0.75) PREP
SCHEMBL7433434 0.95 PREP (0.75) PREP
SCHEMBL7304615 0.85 PREP (1.00) PREP
SCHEMBL7296522 0.85 PREP (1.00) PREP
SCHEMBL7298194 0.83 PREP (0.52) PREPDPP4
SCHEMBL7303286 0.83 PREP (0.72) PREP
SCHEMBL7303791 0.83 PREP (0.72) PREP
SCHEMBL7293276 0.82 PREP (0.94) PREP
SCHEMBL8152338 0.81 PREP (1.00) PREP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0372484-B1 Condensed benzene derivative ZERIA PHARM CO LTD (JP) 1994-10-26 EP disclosed
US-5028604-A Cognition Activators ZERIA PHARMACEUTICAL CO., LTD. (JP) 1991-07-02 US disclosed
EP-0372484-A2 Condensed benzene derivative ZERIA PHARMACEUTICAL CO., LTD. (JP) 1990-06-13 EP disclosed