Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 20/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 20/20 | 0.47 |
| ▸ | PDE2A | O00408 | 4/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7312729 | 0.81 | PDE3B (0.48) | PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL7313288 | 0.81 | PDE3B (0.49) | PDE3BPDE3A | |
| SCHEMBL7311471 | 0.79 | PDE3B (0.49) | PDE3BPDE3A | |
| SCHEMBL7311494 | 0.79 | PDE3B (0.52) | PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL7311008 | 0.78 | PDE3B (0.51) | PDE3BPDE3A | |
| SCHEMBL7321627 | 0.77 | PDE3B (0.73) | PDE3BPDE3A | |
| SCHEMBL7313946 | 0.77 | PDE3B (0.52) | PDE3BPDE3A | |
| SCHEMBL7314397 | 0.76 | PDE3B (0.79) | PDE3BPDE3AP2RY12 | |
| SCHEMBL7312743 | 0.75 | PDE3B (0.63) | PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL7314298 | 0.75 | PDE3B (0.68) | PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |