SCHEMBL7313288

SCHEMBL7313288

CCCCN(C(=O)CCCCCCOc1ccc(F)c2c1CN1C(=N2)NC(=O)C1CO)C1CCCCC1

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDE3B Q13370 20/20 0.49
PDE3A Q14432 20/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7307962 0.82 PDE3B (0.53) PDE3BPDE3A
SCHEMBL7305263 0.81 PDE3B (0.47) PDE3BPDE3A
SCHEMBL7311105 0.79 PDE3B (0.53) PDE3BPDE3A
SCHEMBL7314213 0.79 PDE3B (0.52) PDE3BPDE3A
SCHEMBL7307603 0.79 PDE3B (0.55) PDE3BPDE3A
SCHEMBL7317765 0.79 PDE3B (0.73) PDE3BPDE3A
SCHEMBL7307027 0.78 PDE3B (0.57) PDE3BPDE3A
SCHEMBL7316353 0.77 PDE3B (0.68) PDE3BPDE3A
SCHEMBL7305725 0.77 PDE3B (0.65) PDE3BPDE3A
SCHEMBL7315869 0.76 PDE3B (0.58) PDE3BPDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4670434-A ANTICOAGULANT, INOTROPIC AGENT SYNTEX (U.S.A.) INC. (US) 1987-06-02 US disclosed